I would wish that the distance between Australia and US would decrease to about one hour flying time. Alternately, I would wish for tele-transportation, so that I could visit my family everyday!
My one wish probably changes by the day but at the moment what I would really love is more sleep. Working four days a week and having two young kids who wake up extra early in the morning can be quite draining. I've been told that before I know it they will be teenagers and I won't be able to get them out of bed in the morning!